Vitamin B5

The Benefits of Vitamin B5 (Panthenol) for Skin: Key Findings from Recent Research

Vitamin B5, commonly known as panthenol, has been widely used in skincare for its moisturising and barrier-enhancing effects. Recent studies have provided deeper insights into its effectiveness in supporting skin health, focusing particularly on a new panthenol-containing emollient. Here’s a breakdown of its benefits based on findings from two recent randomised controlled trials.

1. Enhanced Skin Barrier Function

One of the primary benefits of Vitamin B5 in skincare is its ability to improve the skin's barrier function. This recent study used transepidermal water loss (TEWL) as a measure, where a reduction in TEWL signifies a stronger, more resilient skin barrier. Results showed that the panthenol emollient significantly reduced TEWL compared to untreated skin areas. This means it effectively helps the skin retain moisture and resist external irritants, a crucial factor for people with dry or sensitive skin.

2. Improved Skin Hydration

The study measured skin hydration levels using corneometry, which assesses the skin’s water content. In both normal and stressed skin areas, the panthenol emollient consistently increased skin hydration over three weeks. This benefit is especially valuable for individuals dealing with dry or compromised skin conditions, as hydration is vital for maintaining skin softness and elasticity.

3. Restored Lipid Lamellae Structure

Healthy skin relies on a well-organised lipid layer, known as the intercellular lipid lamellae (ICLL), which keeps the skin barrier intact. The study found that regular application of the panthenol emollient led to a significant increase in ICLL length and organisation, indicating a structurally improved barrier. These improvements were sustained even a week after the emollient application stopped, suggesting that panthenol has lasting benefits for skin health.

4. Support for Skin Microbiome Health

Maintaining a balanced skin microbiome is essential for protecting the skin against harmful pathogens. In the study, skin areas treated with the panthenol emollient showed a favourable environment for beneficial bacteria like Micrococcus and Corynebacterium. These microorganisms are known to inhibit pathogenic bacteria and promote a healthy, balanced microbiome, which is increasingly recognized as a cornerstone of healthy skin.

5. Overall Skin Comfort and Tolerance

In both studies, the panthenol emollient was well-tolerated by participants, with minimal side effects. This makes it suitable for daily use, even for people with sensitive skin or conditions like atopic dermatitis.

Conclusion

Vitamin B5 (panthenol) demonstrates significant skin benefits, particularly in terms of hydration, barrier enhancement, and microbiome support. Its ability to strengthen the skin barrier, boost moisture retention, and support a healthy microbial environment positions it as a valuable ingredient for maintaining overall skin health and resilience. For those with dry or sensitive skin, the daily use of a panthenol-based emollient could be an effective strategy for improving skin health and comfort.

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